COPD is an important cause of death and leads to a substantial disability. By the year 2020, COPD might become the fifth-leading cause of combined mortality and disability worldwide. Therefore, determining factors that might influence the course and prognosis of this disease is essential for making treatment decisions. Several studies have been performed to establish parameters associated with an increased risk of death in COPD patients. A low FEV1> and cigarette smoking are the most important factors related to mortality. A number of other variables, such as hypercapnia, hypoxemia, body mass index (BMI), environmental exposures, bronchial responsiveness, a1-antitrypsin deficiency, lower social economic status, and the presence of comorbidities are also considered to be related to poor prognosis. Regarding treatment options, long-term oxygen therapy (LTOT) improves […]

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