Period of responsiveness
The period of effectiveness of tadalafil was assessed in a trial of 348 men with various severities of ED. Men in this doubleblind, placebo-controlled trial were instructed to attempt intercourse on four occasions: twice at roughly 24 h after a dose of either placebo or tadalafil 20 mg, then on two other occasions roughly 36 h after either placebo or tadalafil.
At both 24 h and 36 h after the medication, men who took tadalafil were much more likely to be successful in intercourse attempts (SEP-Q3) than men who received placebo (P<0.001) (Figure 6). Other secondary measures of erectile function and overall satisfaction showed similar improvements with tadalafil. buy levaquin online
These results confirm the findings from the integrated analysis (Figure 3) , showing a prolonged period of responsiveness after the use of tadalafil.
Figure 6) Effect of tadalafil over time (period of responsiveness study). Data from reference 12. SEP-Q3 Sexual Encounter Profile Question 3